1. Zhu Z*, Zhou X, Max Xu, Chen J, Kevin R, Gatphan A,Mark W, C.Allice M, Laura H, Gianpietro D, Liu P. Novel molecular glue degrader function of SPOP inhibitors stabilizes and activates STING to enhance immunotherapy efficacy in melanoma treatment. The Journal of Clinical Investigation. 2025 In press

2. Wang Y*, Deng Y*, Chen J, Quentin H, David U, Zhang Z, Zhang Y, Sarah R, Li L, Laura H, Brian C, Edward M, Blossom D, Anna D, Liu P.  cGAS inhibits ALDH2 to suppress lipid droplet function and regulate MASLD progression. Advvanced Science 2025 e08576

3.  Yu L*, Jin Y*, Chen J, Zhu Z, Su S, Emily W, Joana G, Erica C, Michael M, Liu P. Stable Cas9 expression regulates cell growth by facilitating mTORC2 activation. Nucleic Acids Research. 2025,53,gkaf965

4. Chen J*, Su S*, Oliver A*, Chiarella A, Cloer E, Small G, Ramsden D, Major M, Hathaway N, Gersbach C, Liu P. Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhanced epigenome editing efficiency. Nucleic Acids Research 2024 Vol.52 Oct. 11536-111441.

5. Chen J*, Zhang X, Tan X, Liu P. Somatic gain-of-function mutations in BUD13 promote oncogenesis by disrupting Fbw7 function. Journal of Experimental Medicine. 2023 Vol. 220 No. 10 e20222056. 

6. Chen J*, Bolhuis D, Laggner C, Kong D, Yu L, Wang X, Emanuele M, Brown N, Liu P. Artificial Intelligence-aided OTUD7B inhibitor discovery and validation. Cancers. 2023. January. 15(2): 517

7. Su S*, Chen J*, Jiang Y*, Wang Y, Vital T, Zhang J, Lagger C, Nguyen K, Zhu Z, Prevatte A, Braker N, Herring L, Davis I, Liu P. SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth. Advanced Science. 2021 June. 8: 2004846.

8. Su S*, Chen J*, Wang Y*, Wong L, Zhu Z, Jiang G, Liu P. Lenalidomide downregulates ACE2 protein abundance to alleviate infection by SARS-CoV-2 spike protein conditioned pseudoviruses. Signal Transduction and Targeted Therapy. 2021 May. 6: 182.